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Better Science

VIII. CHALLENGES TO ALTERNATIVES

In addition to the resistance described above, more direct threats to the adoption of alternatives and promotion of animal-based testing protocols may come from massive new testing programs being proposed by such federal regulatory bodies as the Environmental Protection Agency (EPA).

For the past few years, under pressure from politicians as well as consumer and environmental organizations, the EPA has proposed new testing requirements that will kill millions of animals, tailored to:

  • High Production Volume Chemicals (HPV)

  • Endocrine Disruptors (ED)

  • Children's Health Initiative (CHI)

Nearly identical programs have also been proposed for the European Union (REACH) and internationally (OECD). In all cases the respective regulatory agencies have used the new testing mandates to promote existing or create new animal-based testing procedures - usually without the rigorous levels of validation and proof of principle still required for in vitro replacement alternatives. If needed, the new testing requirements could be used as incentives to finally create an alternatives-based, humane approach to assessing human health and safety. The fact that tens of thousands of chemicals have been and continue to be produced without adequate safety/risk assessments is a clear indication of the historical failures of in vivo approaches and not a reason to massively expand such inappropriate approaches to testing.

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Other NEAVS Fact Sheets:
Benefits of Non-Animal Tests | Xenotransplants | Animal Welfare Act | Limitations of Animal Tests | Non-Animal Product Safety Test Alternatives

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Three rats in cage.

In the United States, the Animal Welfare Act (AWA) and Public Health Service (PHS) Policy on Humane Care and Use of Laboratory Animals are the two main regulations governing the use of animals in laboratories.

However
, even with the supposed "protections" afforded by the AWA and PHS Policy, millions of animals suffer and die in unnecessary, counterproductive research.

AWA and PHS regulations for animals in labs are limited in their scope and fraught with loopholes that continue to allow for both physical and psychological cruelty and suffering.